PubMed Publications
2024 year
1: Wu J, Jin M, Tran Q, Kim M, Kim SI, Shin J, Park H, Shin N, Kang H, Shin HJ, Lee SY, Cui SB, Lee CJ, Lee WH, Kim DW*.
Employing the sustained-release properties of poly(lactic-co-glycolic acid) nanoparticles to reveal a novel mechanism of sodium-hydrogen exchanger 1 in neuropathic pain.
Transl Res. 2024 Jan;263:53-72.
doi: 10.1016/j.trsl.2023.09.003. Epub 2023 Sep 9. PMID: 37678757.
IF=7.8
2: Shin HJ, Choi SG, Qu F, Yi MH, Lee CH, Kim SR, Kim HG, Beom J, Yi Y, Kim DK, Joe EH, Song HJ, Kim Y, Kim DW.
Peptide-mediated targeted delivery of SOX9 nanoparticles into astrocytes ameliorates ischemic brain injury.
Nanoscale. 2024 Jan 3;16(2):833-847.
doi: 10.1039/d3nr01318a. PMID: 38093712.
IF=8.2
Rejuvenating aged microglia by p16ink4a-siRNA-loaded nanoparticles increases amyloid-β clearance in animal models of Alzheimer's disease.
Mol Neurodegener. 2024 Mar 16;19(1):25.
doi: 10.1186/s13024-024-00715-x. PMID: 38493185.
IF=15.1
doi: 10.1186/s13024-024-00715-x. PMID: 38493185.
IF=15.1
https://rdcu.be/dBtAz
5: Kim SI, Yang J, Shin J, Shin N, Shin HJ, Lee J, Noh C, Kim DW*, Lee SY.
4: Hwang JA, Choi SK, Kim SH, Kim DW*.
Pharmacological Inhibition of LRRK2 Exhibits Neuroprotective Activity in Mouse Photothrombotic Stroke Model.
Exp Neurobiol. 2024 Feb 29;33(1):36-45.
doi: 10.5607/en23023. PMID: 38471803; PMCID: PMC10938073.
IF=2.4
5: Kim SI, Yang J, Shin J, Shin N, Shin HJ, Lee J, Noh C, Kim DW*, Lee SY.
Amitriptyline nanoparticle repositioning prolongs the anti-allodynic effect of enhanced microglia targeting.
Nanomedicine (Lond). 2024;19(25):2099-2112.
doi: 10.1080/17435889.2024.2390349. Epub 2024 Sep 4. PMID: 39229790; PMCID: PMC11485917.
1. Kyung H, Park Y, Oh SH, Kim DW, Seo YJ, Song SH.
Effects of Midcheek Lift According to Dissection Plane and Range: An Anatomical Study.
Aesthet Surg J. 2024 Apr 4;44(5):473-481.
doi: 10.1093/asj/sjad378. PMID: 38124346.
2. Kang DY, Jang Y, Lee H, Lee J, Kang M, Kim DW, Lee S, Lee S.
Optogenetic STING clustering system through nanobody-fused photoreceptor for innate immune regulation.
Sensors and Actuators: B. Chemical 399 (2024) 134822
The antipsychotic chlorpromazine reduces neuroinflammation by inhibiting microglial voltage-gated potassium channels.
Glia. 2024 Oct 22.
doi: 10.1002/glia.24629. Epub ahead of print. PMID: 39435609.
1. 별아교세포 선택적 펩타이드가 결합된 나노입자 및 이의 용도
10-2629203 (2024.01.22)
10-2021-0069959 (2021.05.31)
10-2021-0069959 (2021.05.31)
Nanoparticle conjugated with astrocyte-selective peptide and uses thereof
김동운, 신효정2023 year
Patent
산소수를 포함하는 뇌전증성 발작 또는 경련의 예방, 개선 또는 치료용 조성물
김동운/강준원/송희정/권혁희
등록번호: 10-2607681
1: Choi SG, Shin J, Lee KY, Park H, Kim SI, Yi YY, Kim DW*, Song HJ, Shin HJ.
PINK1 siRNA-loaded poly(lactic-co-glycolic acid) nanoparticles provide neuroprotection in a mouse model of photothrombosis-induced ischemic stroke.
Glia. 2023 May;71(5):1294-1310.
doi: 10.1002/glia.24339. Epub 2023 Jan 18. PMID: 36655313.
IF = 8.043 (2021)
2: Hwang P, Shin CM, Sherwood JA, Kim D, Vijayan VM, Josyula KC, Millican RC, Ho D, Brott BC, Thomas V, Choi CH, Oh SH, Kim DW*, Jun HW.
A multi-targeting bionanomatrix coating to reduce capsular contracture development on silicone implants.
Biomater Res. 2023 Apr 22;27(1):34.
doi: 10.1186/s40824-023-00378-7. PMID: 37087537; PMCID: PMC10122329.
IF=15.86
3. Park H, Lee JS, Lee N, Kwon K, Kim JB, Kim SB, Kim HG, Kim DW*
Red stem of spinach promotes antioxidant and anti-inflammatory chondroprotection in a rat model of osteoarthritis
Journal of Functional Foods Volume 109, October 2023, 105789
IF=5.6
1: Choi SJ, Kim S, Lee WS, Kim DW, Kim CS, Oh SH.
Autophagy Dysfunction in a Diabetic Peripheral Neuropathy Model.
Plast Reconstr Surg. 2023 Feb 1;151(2):355-364.
doi: 10.1097/PRS.0000000000009844. Epub 2022 Nov 11. PMID: 36355029.
2: Ho D, Lynd TO, Jun C, Shin J, Millican RC, Estep BK, Chen J, Zhang X, Brott BC, Kim DW, Sherwood JA, Hwang PTJ.
MiR-146a encapsulated liposomes reduce vascular inflammatory responses through decrease of ICAM-1 expression, macrophage activation, and foam cell formation.
Nanoscale. 2023 Feb 16;15(7):3461-3474.
doi: 10.1039/d2nr03280e. PMID: 36723042.
3: Piao S, Lee I, Kim S, Park H, Nagar H, Choi SJ, Vu GH, Kim M, Lee EO, Jeon BH, Kim DW, Seo Y, Kim CS.
CRIF1 siRNA-Encapsulated PLGA Nanoparticles Suppress Tumor Growth in MCF-7 Human Breast Cancer Cells.
Int J Mol Sci. 2023 Apr 18;24(8):7453.
doi: 10.3390/ijms24087453. PMID: 37108616; PMCID: PMC10138627.
산소수를 포함하는 뇌전증성 발작 또는 경련의 예방, 개선 또는 치료용 조성물
김동운/강준원/송희정/권혁희
등록번호: 10-2607681
등록일자: 2023. 11. 24
출원번호 10-2020-0119033
출원일 2020.09.1
2022 year
1: Park H, Lee HR, Shin HJ, Park JA, Joo Y, Kim SM, Beom J, Kang SW, Kim DW*, Kim J.
p16INK4a-siRNA nanoparticles attenuate cartilage degeneration in osteoarthritis by inhibiting inflammation in fibroblast-like synoviocytes.
Biomater Sci. 2022 Jun 14;10(12):3223-3235. doi: 10.1039/d1bm01941d.PMID: 35579255
IF = 7.590 (2021)
2: Tran Q, Pham TL, Shin HJ, Shin J, Shin N, Kwon HH, Park H, Kim SI, Choi SG, Wu J, Ngo VTH, Park JB, Kim DW*.
Targeting spinal microglia with fexofenadine-loaded nanoparticles prolongs pain relief in a rat model of neuropathic pain.
Nanomedicine. 2022 Jun 14:102576.
doi: 10.1016/j.nano.2022.102576. Epub ahead of print. PMID: 35714922.
IF = 6.096 (2021)
3. Shin HJ, Lee KY, Kang JW, Choi SG, Kim DW*, Yi YY
Perampanel Reduces Brain Damage via Induction of M2 Microglia in a Neonatal Rat Stroke ModelInt J Nanomedicine. 2022 Jun 27;17:2791-2804.
doi: 10.2147/IJN.S361377. PMID: 35782016; PMCID: PMC9248959.
IF = 7.033 (2021)
4. Chau Nguyen TT, Shin CM, Lee SJ, Koh ES, Kwon HH, Park H, Kim DH, Choi CH, Oh SH, Kim DW*, Yang SY.
Ultrathin Nanostructured Films of Hyaluronic Acid and Functionalized β-Cyclodextrin Polymer Suppress Bacterial Infection and Capsular Formation of Medical Silicone Implants.
Biomacromolecules. 2022 Nov 14;23(11):4547-4561.
doi: 10.1021/acs.biomac.2c00687. Epub 2022 Sep 21.PMID: 36130109
IF = 6.979 (2021)
5. Kim Y, Choi HN, Kim T, Kim SJ, Kim Y, Kim JS, Lee S, Goo YT, Kim DW*, Lee SD
Corn Silk Extract Prevents Carrageenan-Induced Inflammatory Edema
Food Suppl Biomater Health. 2022 Mar;2(1):e9. English.
Published online Mar 31, 2022. https://doi.org/10.52361/fsbh.2022.2.e9
저서
Prize
2. Shin HJ, Park H, Shin N, Kwon HH, Yin Y, Hwang JA, Kim SI, Kim SR, Kim S, Joo Y, Kim Y, Kim J, Beom J, Kim DW*.
doi: 10.3390/polym12051014. PMID: 32365512; PMCID: PMC7284875.
https://doi.org/10.3390/polym12051014
6. Yi YY, Shin HJ, Choi SG, Kang JW, Song HJ, Kim SK, Kim DW*.
BMAL1 Suppresses Proliferation, Migration, and Invasion of U87MG Cells by Downregulating Cyclin B1, Phospho-AKT, and Metalloproteinase-9.
Int J Mol Sci. 2020 Mar 28;21(7). pii: E2352.
doi: 10.3390/ijms21072352. PubMed PMID: 32231148; PubMed Central PMCID: PMC7178273.
Food Suppl Biomater Health. 2022 Mar;2(1):e9. English.
Published online Mar 31, 2022. https://doi.org/10.52361/fsbh.2022.2.e9
1. Kim S, Moon GJ, Kim HJ, Kim DG, Kim J, Nam Y, Sharma C, Leem E, Lee S, Kim KS, Ha CM, McLean C, Jin BK, Shin WH, Kim DW, Oh YS, Hong CW, Kim SR.
Control of hippocampal pKr-2 expression reduces neurotoxic symptoms in 5XFAD mice.
Br J Pharmacol. 2022 Mar;179(5):998-1016. doi: 10.1111/bph.15681. Epub 2021 Oct 24.PMID: 34524687
2: Kwon HH, Jung SY, Park H, Shin HJ, Kim DW, Song HJ, Kang JW.
Oxygenated Water Increases Seizure Threshold in Various Rodent Seizure Models.
Int J Mol Sci. 2022 Nov 16;23(22):14124.
doi: 10.3390/ijms232214124. PMID: 36430603.
1. 의과학실험방법론 Protocols in Medical Science
허강민 송창화 김동운 외 11인, 충남대학교 출판원 2022
2022.3.2 ISBN 979-11-6503-0
2. 최신의학통계학 Trends in Medical Statistics
박종선, 김동운, 권인선, 이영호, 충남대학교 출판원 2022
2022. 8.24 ISBN 979-11-6503-164-4
3. 기초의과학생물정보학 Bioinformatics for Basic Medical Sciences
박종선, 김동운, 구윤서, 이동헌, 홍성태, 차광호, 충남대학교 출판원 2022
2022.8.24 ISBN 979-11-6503-165-7
기술이전
1. 메틸아데닌을 유효성분으로 함유하는 신경병증성통증의 억제 또는 치료용 조성물(10-1448155)
코스바이오사이언스 (3,300,000), 2022.04.13. 양도
2. p38 또는 이를 코딩하는 유전자의 발현을 억제하는 제제가 함유된 나노입자를 포함하는 신경병증성 통증 예방 또는 치료용 조성물(10-2113090)
나노글리아 (22,000,000) 2022.09.07. 양도
2021 year
1: Hwang JA, Shin N, Shin HJ, Yin Y, Kwon HH, Park H, Shin J, Kim SI, Kim DW*, Song HJ.
Protective Effects of ShcA Protein Silencing for Photothrombotic Cerebral Infarction.
Transl Stroke Res. 2021 Oct;12(5):866-878.
doi: 10.1007/s12975-020-00874-1. Epub 2020 Nov 26.PMID: 33242144
IF = 6.829 (2020)
2: Kwon HH, Lee JS, Park H, Shin J, Yin Y, Shin N, Shin HJ, Hwang JA, Kim DW*, Kang JW.
Vitamin E reduces spasms caused by prenatal stress by lowering calpain expression.
Epilepsy Behav. 2021 Jan;114(Pt A):107609.
doi: 10.1016/j.yebeh.2020.107609. Epub 2020 Nov 27. PMID: 33257295.
IF = 3.045 (2020)
3: Kim SI, Shin J, Tran Q, Park H, Kwon HH, Shin N, Hwang JA, Shin HJ, Lee J, Lee WH, Lee SY, Kim DW*.
Application of PLGA nanoparticles to enhance the action of duloxetine on microglia in neuropathic pain.
Biomater Sci. 2021 Sep 14;9(18):6295-6307.
doi: 10.1039/d1bm00486g. PMID: 34378557.
IF = 6.843 (2020)
1: Shin CM, Cho S, Kim DH, Ha Y, Shin HJ, Shin N, Kim DW, Choi CH, Cho WK, Oh SH.
Zwitterionic polydopamine coatings suppress silicone implant-induced capsule formation.
Biomater Sci. 2021 May 4;9(9):3425-3432.
doi: 10.1039/d0bm02215b. PMID: 33949402.
2: Gwon DH, Kim SI, Lee SH, Noh C, Kim Y, Yun S, Lee WH, Oh JY, Kim DW, Hong J, Lee SY.
NFAT5 Deficiency Alleviates Formalin-Induced Inflammatory Pain Through mTOR.
Int J Mol Sci. 2021 Mar 4;22(5):2587.
doi: 10.3390/ijms22052587. PMID: 33806698; PMCID: PMC7961436.
3: Lee J, Kwon YE, Kim J, Kim DW, Guim H, Yeon J, Kim JC, Choi JS.
Nonviral gene delivery using PAMAM dendrimer conjugated with the nuclear localization signal peptide derived from human papillomavirus type 11 E2 protein.
J Biomater Sci Polym Ed. 2021 Jun;32(9):1140-1160. doi: 10.1080/09205063.2021.1909411. Epub 2021 Apr 19.
7: Shin HJ, Lee KY, Kwon K, Kwon OY, Kim DW
4: Lee S, Shin HJ, Noh C, Kim SI, Ko YK, Lee SY, Lim C, Hong B, Yang SY, Kim DW, Lee WH, Kim YH.
IKBKB siRNA-Encapsulated Poly (Lactic-co-Glycolic Acid) Nanoparticles Diminish Neuropathic Pain By Inhibiting Microglial Activation.
Int J Mol Sci. 2021 May 26;22(11):5657.
doi: 10.3390/ijms22115657. PMID: 34073390.
5: Cho JH, Lee JS, Kim HG, Lee HW, Fang Z, Kwon HH, Kim DW, Lee CM, Jeong JW.
Ethyl Acetate Fraction of Amomum villosum var. xanthioides Attenuates Hepatic Endoplasmic reticulum Stress-Induced Non-Alcoholic Steatohepatitis via Improvement of Antioxidant Capacities.
Antioxidants (Basel). 2021 Jun 23;10(7):998.
doi: 10.3390/antiox10070998. PMID: 34201527; PMCID: PMC8300789.
6: Lee JS, Lee SB, Kim DW, Shin N, Jeong SJ, Yang CH, Son CG.
Social isolation-related depression accelerates ethanol intake via microglia-derived
neuroinflammation.
Sci Adv. 2021 Nov 5;7(45):eabj3400.
doi:10.1126/sciadv.abj3400. Epub 2021 Nov 5. PMID: 34739315.
Development of PLGA Nanoparticles for Astrocyte-specific Delivery of Gene Therapy: A Review
Journal of Life Science 2021 Vol. 31. No. 9. 849~855
2021 충남대학교 우수강의교수 총장상
2021.1.4
2021 충남대학교병원 의학연구학술상 기초의학부문
2021.12.08 (2021-04)
Patent
1. PAT4를 포함하는 만성통증 질환 예방, 개선 또는 치료용 조성물
1. PAT4를 포함하는 만성통증 질환 예방, 개선 또는 치료용 조성물
출원번호:10-2019-0033788 (2019.03.25)
등록번호: 10-2213878 (2021.02.02)
김동운, 홍진표, 이선열, 윤옥화
등록번호: 10-2213878 (2021.02.02)
김동운, 홍진표, 이선열, 윤옥화
2020 year
1. Yin Y, Phạm TL, Shin J, Shin N, Kang DW, Lee SY, Lee W, Kim CS, Kim SR, Hong J, Kim DW*.
Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice.
J Clin Med. 2020 Jan 22;9(2). pii: E305.
doi: 10.3390/jcm9020305. PubMed PMID: 31979015.
1. Yin Y, Phạm TL, Shin J, Shin N, Kang DW, Lee SY, Lee W, Kim CS, Kim SR, Hong J, Kim DW*.
Arginase 2 Deficiency Promotes Neuroinflammation and Pain Behaviors Following Nerve Injury in Mice.
J Clin Med. 2020 Jan 22;9(2). pii: E305.
doi: 10.3390/jcm9020305. PubMed PMID: 31979015.
2. Shin HJ, Park H, Shin N, Kwon HH, Yin Y, Hwang JA, Kim SI, Kim SR, Kim S, Joo Y, Kim Y, Kim J, Beom J, Kim DW*.
p47phox siRNA-Loaded PLGA Nanoparticles Suppress
ROS/Oxidative Stress-Induced Chondrocyte Damage in Osteoarthritis.
Polymers
(Basel). 2020 Feb 13;12(2). pii: E443.
doi: 10.3390/polym12020443. PubMed PMID:
32069893.
https://www.mdpi.com/2073-4360/12/2/443
3: Shin HJ, Park H, Shin N, Shin J, Gwon DH, Kwon HH, Yin Y, Hwang JA, Hong J, Heo JY, Kim CS, Joo Y, Kim Y, Kim J, Beom J, Kim DW*.
p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis.
Int J Nanomedicine. 2020 Apr 8;15:2379-2390.
doi: 10.2147/IJN.S234198. eCollection 2020. PubMed PMID: 32308389; PubMed Central PMCID: PMC7152540.
4:Phạm TL, Yin Y, Kwon HH, Shin N, Kim SI, Park H, Shin J, Shin HJ, Hwang JA, Song HJ, Kim SR, Lee JH, Hwang PTJ, Jun HW, Kim DW*.
miRNA 146a-5p-loaded poly(d,l-lactic-co-glycolic acid) nanoparticles impair pain behaviors by inhibiting multiple inflammatory pathways in microglia.
Nanomedicine (Lond). 2020 May;15(11):1113-1126.
doi: 10.2217/nnm-2019-0462. Epub 2020 Apr 15. PMID: 32292108.
5. Shin N, Shin HJ, Yi Y, Beom J, Lee W, Lee CH, Kim DW*
p66shc siRNA-Encapsulated PLGA Nanoparticles Ameliorate Neuropathic Pain Following Spinal Nerve Ligation
Polymers (Basel). 2020 Apr 29;12(5):1014.https://www.mdpi.com/2073-4360/12/2/443
3: Shin HJ, Park H, Shin N, Shin J, Gwon DH, Kwon HH, Yin Y, Hwang JA, Hong J, Heo JY, Kim CS, Joo Y, Kim Y, Kim J, Beom J, Kim DW*.
p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis.
Int J Nanomedicine. 2020 Apr 8;15:2379-2390.
doi: 10.2147/IJN.S234198. eCollection 2020. PubMed PMID: 32308389; PubMed Central PMCID: PMC7152540.
4:Phạm TL, Yin Y, Kwon HH, Shin N, Kim SI, Park H, Shin J, Shin HJ, Hwang JA, Song HJ, Kim SR, Lee JH, Hwang PTJ, Jun HW, Kim DW*.
miRNA 146a-5p-loaded poly(d,l-lactic-co-glycolic acid) nanoparticles impair pain behaviors by inhibiting multiple inflammatory pathways in microglia.
Nanomedicine (Lond). 2020 May;15(11):1113-1126.
doi: 10.2217/nnm-2019-0462. Epub 2020 Apr 15. PMID: 32292108.
5. Shin N, Shin HJ, Yi Y, Beom J, Lee W, Lee CH, Kim DW*
p66shc siRNA-Encapsulated PLGA Nanoparticles Ameliorate Neuropathic Pain Following Spinal Nerve Ligation
doi: 10.3390/polym12051014. PMID: 32365512; PMCID: PMC7284875.
https://doi.org/10.3390/polym12051014
6. Yi YY, Shin HJ, Choi SG, Kang JW, Song HJ, Kim SK, Kim DW*.
Preventive Effects of Neuroprotective Agents in a Neonatal Rat of Photothrombotic Stroke Model
Int J Mol Sci. 2020 May 24;21(10):E3703.
doi: 10.3390/ijms21103703. PMID: 32456353.
7. Phạm TL, Kim DW*.
Poly(lactic-co-glycolic acid) nanomaterial-based treatment options for pain management: a review.
Nanomedicine (Lond). 2020 Aug 6.
doi: 10.2217/nnm-2020-0114. Epub ahead of print. PMID: 32757701.
Int J Mol Sci. 2020 May 24;21(10):E3703.
doi: 10.3390/ijms21103703. PMID: 32456353.
7. Phạm TL, Kim DW*.
Poly(lactic-co-glycolic acid) nanomaterial-based treatment options for pain management: a review.
Nanomedicine (Lond). 2020 Aug 6.
doi: 10.2217/nnm-2020-0114. Epub ahead of print. PMID: 32757701.
8. Park H, Hong J, Yin Y, Joo Y, Kim Y, Shin J, Kwon HH, Shin N, Shin HJ, Beom J, Kim DW*, Kim J.
TAP2, a peptide antagonist of Toll-like receptor 4, attenuates pain and cartilage degradation in a monoiodoacetate-induced arthritis rat model.
Sci Rep. 2020 Oct 15;10(1):17451.
doi: 10.1038/s41598-020-74544-5. PMID: 33060735; PMCID: PMC7567100
1. Jeon MT, Moon GJ, Kim S, Choi M, Oh YS, Kim DW, Kim HJ, Lee KJ, Choe Y, Ha CM, Jang IS, Nakamura M, McLean C, Chung WS, Shin WH, Lee SG, Kim SR.
Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo.
Br J Pharmacol. 2020 Feb;177(3):668-686.
doi: 10.1111/bph.14882. Epub 2019 Dec 27. PubMed PMID: 31658360.
Neurotrophic interactions between neurons and astrocytes following AAV1-Rheb(S16H) transduction in the hippocampus in vivo.
Br J Pharmacol. 2020 Feb;177(3):668-686.
doi: 10.1111/bph.14882. Epub 2019 Dec 27. PubMed PMID: 31658360.
2. Kim S, Piao S, Lee I, Nagar H, Choi SJ, Shin N, Kim DW, Shong M, Jeon BH, Kim CS.
CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells.
Free Radic Biol Med. 2020 Apr;150:161-171.
doi: 10.1016/j.freeradbiomed.2020.02.017. Epub 2020 Feb 25. PMID: 32109515.
3: Gwon DH, Lee WY, Shin N, Kim SI, Jeong K, Lee WH, Kim DW, Hong J, Lee SY. BMAL1 Suppresses Proliferation, Migration, and Invasion of U87MG Cells by Downregulating Cyclin B1, Phospho-AKT, and Metalloproteinase-9.
Int J Mol Sci. 2020 Mar 28;21(7). pii: E2352.
doi: 10.3390/ijms21072352. PubMed PMID: 32231148; PubMed Central PMCID: PMC7178273.
4. Pandit S, Neupane C, Woo J, Sharma R, Nam MH, Lee GS, Yi MH, Shin N, Kim DW, Cho H, Jeon BH, Kim HW, Lee CJ, Park JB.
Bestrophin1-mediated tonic GABA release from reactive astrocytes prevents the development of seizure-prone network in kainate-injected hippocampi.
Glia. 2020 May;68(5):1065-1080.
doi: 10.1002/glia.23762.
5. Sun MY, Jeon A, Seo CM, Kim YG, Wu YN, Kim DW, Lee JH.
The injection site inthe tarsal tunnel to minimize neurovascular injury for heel pain: an anatomical study.
Surg Radiol Anat. 2020 Jun;42(6):681-684.
doi: 10.1007/s00276-019-02411-8. Epub 2020 Jan 14. PubMed PMID: 31938852.
6. Noh C, Shin HJ, Lee S, Kim SI, Kim YH, Lee WH, Kim DW, Lee SY, Ko YK
CX3CR1-Targeted PLGA Nanoparticles Reduce Microglia Activation and Pain Behavior in Rats with Spinal Nerve Ligation
Bestrophin1-mediated tonic GABA release from reactive astrocytes prevents the development of seizure-prone network in kainate-injected hippocampi.
Glia. 2020 May;68(5):1065-1080.
doi: 10.1002/glia.23762.
5. Sun MY, Jeon A, Seo CM, Kim YG, Wu YN, Kim DW, Lee JH.
The injection site inthe tarsal tunnel to minimize neurovascular injury for heel pain: an anatomical study.
Surg Radiol Anat. 2020 Jun;42(6):681-684.
doi: 10.1007/s00276-019-02411-8. Epub 2020 Jan 14. PubMed PMID: 31938852.
6. Noh C, Shin HJ, Lee S, Kim SI, Kim YH, Lee WH, Kim DW, Lee SY, Ko YK
CX3CR1-Targeted PLGA Nanoparticles Reduce Microglia Activation and Pain Behavior in Rats with Spinal Nerve Ligation
Int. J. Mol. Sci. 2020, 21(10), 3469
https://doi.org/10.3390/ijms21103469
7. Ji-Hye Song, Kisang Kwon, Nuri Lee, Hyojung Shin, Dong Woon Kim, Honggeun Kim, and Ans O-Yu Kwon
7. Ji-Hye Song, Kisang Kwon, Nuri Lee, Hyojung Shin, Dong Woon Kim, Honggeun Kim, and Ans O-Yu Kwon
cDNA Cloning and Expression Analysis of Troponin C from Gryllus bimaculatus (Orthoptera: Gryllidae)
Journal of the Kansas Entomological Society 92(3), 536-548, (8 June 2020). https://doi.org/10.2317/0022-8567-92.3.536
8. Eom TM, Kwon HH, Shin N, Kim DW, Fang Z, Seol IC, Kim YS, Kim HG, Yoo HR.
Traditional Korean herbal formulae, Yuk-Mi-Ji-Hwang-Tang, ameliorates impairment of hippocampal memory ability by chronic restraint stress of mouse model.
J Ethnopharmacol. 2020 Jun 13:113102.
doi: 10.1016/j.jep.2020.113102.
9. Yoon D, Jeon MT, Woon Kim D, Kim SR.
8. Eom TM, Kwon HH, Shin N, Kim DW, Fang Z, Seol IC, Kim YS, Kim HG, Yoo HR.
Traditional Korean herbal formulae, Yuk-Mi-Ji-Hwang-Tang, ameliorates impairment of hippocampal memory ability by chronic restraint stress of mouse model.
J Ethnopharmacol. 2020 Jun 13:113102.
doi: 10.1016/j.jep.2020.113102.
9. Yoon D, Jeon MT, Woon Kim D, Kim SR.
Treatment with AAV1-Rheb(S16H) provides neuroprotection in a mouse model of photothrombosis-induced ischemic stroke.
Neuroreport. 2020 Sep 9;31(13):971-978.
doi: 10.1097/WNR.0000000000001506. PMID:32694311.
Neuroreport. 2020 Sep 9;31(13):971-978.
doi: 10.1097/WNR.0000000000001506. PMID:32694311.
10. Park HJ, Hong J, Piao Y, Shin HJ, Lee SJ, Rhyu IJ, Yi MH, Kim J, Kim DW, Beom J.
Extracorporeal shockwave therapy enhances peripheral nerve remyelination and gait function in a crush model.
Adv Clin Exp Med. 2020 Jul;29(7):819-824.
Extracorporeal shockwave therapy enhances peripheral nerve remyelination and gait function in a crush model.
Adv Clin Exp Med. 2020 Jul;29(7):819-824.
doi: 10.17219/acem/122177. PMID: 32735402.
Prize
2020. 1. 2. Chungnam National University Presidential Award
Patent
1. USA
Application No. 15/911,391 (03/05/2018)
Patent No. 10624866 (04/21/2020)
Composition for prevention or treatment of chronic pain comprising evans blue
2. p38 또는 이를 코딩하는 유전자의 발현을 억제하는 제제가 함유된 나노입자를 포함하는 신경병증성 통증 예방 또는 치료용 조성물
출원번호:10-2018-0090489 (2018.08.02)
등록번호:10-2113090 (2020.5.14)
김동운, 홍진표, 이선열, 신주희
3. Foxp3 또는 이를 코딩하는 유전자를 포함하는 나노입자 및 이의 용도
출원번호: 10-2019-0031714 (2019.03.20)
등록번호: 10-2118116 (2020.05.27)
김동운, 홍진표, 이선열, 신주희
4. 뇌종양 발명의 명칭 진단 또는 예후 예측용 바이오마커 조성물
2020. 1. 2. Chungnam National University Presidential Award
1. USA
Application No. 15/911,391 (03/05/2018)
Patent No. 10624866 (04/21/2020)
Composition for prevention or treatment of chronic pain comprising evans blue
2. p38 또는 이를 코딩하는 유전자의 발현을 억제하는 제제가 함유된 나노입자를 포함하는 신경병증성 통증 예방 또는 치료용 조성물
출원번호:10-2018-0090489 (2018.08.02)
등록번호:10-2113090 (2020.5.14)
김동운, 홍진표, 이선열, 신주희
3. Foxp3 또는 이를 코딩하는 유전자를 포함하는 나노입자 및 이의 용도
출원번호: 10-2019-0031714 (2019.03.20)
등록번호: 10-2118116 (2020.05.27)
김동운, 홍진표, 이선열, 신주희
4. 뇌종양 발명의 명칭 진단 또는 예후 예측용 바이오마커 조성물
출원번호: 10-2019-0046039 (2019.04.19)
등록번호: 10-2177269-0000 (2020.11.04)
김동운/조상연
2019 year
등록번호: 10-2177269-0000 (2020.11.04)
김동운/조상연
2019 year
2019.4.17 Nanoglia Company was founded
1. Shin N, Kim HG, Shin HJ, Kim S, Kwon HH, Baek H, Yi MH, Zhang E, Kim JJ, Hong J, Lee SY, Lee W, Triantafillu UL, Kim CS, Kim Y, Kim DW*.
1. Shin N, Kim HG, Shin HJ, Kim S, Kwon HH, Baek H, Yi MH, Zhang E, Kim JJ, Hong J, Lee SY, Lee W, Triantafillu UL, Kim CS, Kim Y, Kim DW*.
Uncoupled Endothelial
Nitric Oxide Synthase Enhances p-Tau in Chronic Traumatic Encephalopathy Mouse
Model.
Antioxid Redox Signal. 2019 May 1;30(13):1601-1620.
doi:
10.1089/ars.2017.7280. Epub 2018 Sep 7. PubMed PMID: 30070145.
2. Cho SY, Kim S, Kim G, Singh P, Kim DW*.
Integrative analysis of KIF4A, 9, 18A,
and 23 and their clinical significance in low-grade glioma and glioblastoma.
Sci
Rep. 2019 Mar 14;9(1):4599.
doi: 10.1038/s41598-018-37622-3. PubMed PMID: 30872592.
https://doi.org/10.1038/s41598-018-37622-3
3. Shin J, Yin Y, Kim DK, Lee SY, Lee W, Kang JW, Kim DW*, Hong J.
https://doi.org/10.1038/s41598-018-37622-3
3. Shin J, Yin Y, Kim DK, Lee SY, Lee W, Kang JW, Kim DW*, Hong J.
Foxp3
plasmid-encapsulated PLGA nanoparticles attenuate pain behavior in rats with
spinal nerve ligation.
Nanomedicine. 2019 Mar 8. pii: S1549-9634(19)30054-1.
doi:
10.1016/j.nano.2019.02.023. [Epub ahead of print] PubMed PMID: 30858084.
https://doi.org/10.1016/j.nano.2019.02.023
4. Yi MH, Shin J, Shin N, Yin Y, Lee SY, Kim CS, Kim SR, Zhang E, Kim DW*.
https://doi.org/10.1016/j.nano.2019.02.023
4. Yi MH, Shin J, Shin N, Yin Y, Lee SY, Kim CS, Kim SR, Zhang E, Kim DW*.
PINK1 mediates spinal cord mitophagy in neuropathic pain.
J Pain Res. 2019 May 28;12:1685-1699.
doi: 10.2147/JPR.S198730. eCollection 2019. Erratum in: J Pain Res. 2019 Aug 27;12:2627. PubMed PMID: 31239755; PubMed Central PMCID: PMC6554001.
5. Yin Y, Park H, Lee SY, Lee WH, Song HJ, Kim J, Kim DW*, Hong J.
doi: 10.2147/JPR.S198730. eCollection 2019. Erratum in: J Pain Res. 2019 Aug 27;12:2627. PubMed PMID: 31239755; PubMed Central PMCID: PMC6554001.
5. Yin Y, Park H, Lee SY, Lee WH, Song HJ, Kim J, Kim DW*, Hong J.
Analgesic Effect of Toll-like Receptor 4 Antagonistic Peptide 2 on Mechanical Allodynia Induced with Spinal Nerve Ligation in Rats.
Exp Neurobiol. 2019 Jun;28(3):352-361.
doi: 10.5607/en.2019.28.3.352. Epub 2019 Jun 26. PubMed PMID: 31308795; PubMed Central PMCID: PMC6614064.
6. Kwon HH, Neupane C, Shin J, Gwon DH, Yin Y, Shin N, Shin HJ, Hong J, Park JB, Yi Y, Kim DW*, Kang JW.
doi: 10.5607/en.2019.28.3.352. Epub 2019 Jun 26. PubMed PMID: 31308795; PubMed Central PMCID: PMC6614064.
6. Kwon HH, Neupane C, Shin J, Gwon DH, Yin Y, Shin N, Shin HJ, Hong J, Park JB, Yi Y, Kim DW*, Kang JW.
Calpain-2 as a Treatment Target in Prenatal Stress-induced Epileptic Spasms in Infant Rats.
Exp Neurobiol. 2019 Aug 31;28(4):529-536.
doi: 10.5607/en.2019.28.4.529. PubMed PMID: 31495081.
7. Yin Y, Hong J, Phạm TL, Shin J, Gwon DH, Kwon HH, Shin N, Shin HJ, Lee SY, Lee WH, Kim DW*.
doi: 10.5607/en.2019.28.4.529. PubMed PMID: 31495081.
7. Yin Y, Hong J, Phạm TL, Shin J, Gwon DH, Kwon HH, Shin N, Shin HJ, Lee SY, Lee WH, Kim DW*.
Evans Blue Reduces Neuropathic Pain Behavior by Inhibiting Spinal ATP
Release.
Int J Mol Sci. 2019 Sep 9;20(18). pii: E4443.
doi: 10.3390/ijms20184443. PubMed PMID: 31505901.
8. Shin HJ, Park H, Shin N, Kwon HH, Yin Y, Hwang JA, Song HJ, Kim J, Kim DW*, Beom J.
doi: 10.3390/ijms20184443. PubMed PMID: 31505901.
8. Shin HJ, Park H, Shin N, Kwon HH, Yin Y, Hwang JA, Song HJ, Kim J, Kim DW*, Beom J.
Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage
Degeneration in Osteoarthritis.
J Clin Med. 2019 Nov 2;8(11). pii: E1849.
doi:
10.3390/jcm8111849. PubMed PMID: 31684073.
2. Kwon JY, Jeon MT, Jung UJ, Kim DW, Moon GJ, Kim SR.
Therapeutic Potential of Flavonoids as Alternative Medicines in Epilepsy.
Adv Nutr. 2019 May 21. pii: nmz047.
doi: 10.1093/advances/nmz047. [Epub ahead of print] PubMed PMID: 31111873.
1. Leem E, Oh YS, Shin WH, Jin BK, Jeong JY, Shin M, Kim DW, Jang JH, Kim HJ, Ha CM, Jung UJ, Moon GJ, Kim SR.
Effects of Silibinin Against Prothrombin Kringle-2-Induced Neurotoxicity in the Nigrostriatal Dopaminergic System In Vivo.
J Med Food. 2019 Mar;22(3):277-285.
J Med Food. 2019 Mar;22(3):277-285.
doi: 10.1089/jmf.2018.4266. Epub 2019 Jan 11. PubMed PMID: 30632945.
2. Kwon JY, Jeon MT, Jung UJ, Kim DW, Moon GJ, Kim SR.
Therapeutic Potential of Flavonoids as Alternative Medicines in Epilepsy.
Adv Nutr. 2019 May 21. pii: nmz047.
doi: 10.1093/advances/nmz047. [Epub ahead of print] PubMed PMID: 31111873.
2018 year
1: Piao Y, Gwon DH, Kang DW, Hwang TW, Shin N, Kwon HH, Shin HJ, Yin Y, Kim JJ, Hong J, Kim HW, Kim Y, Kim SR, Oh SH, Kim DW*.
4. Choi SJ, Piao S, Nagar H, Jung SB, Kim S, Lee I, Kim SM, Song HJ, Shin N, Kim DW, Irani K, Jeon BH, Park JW, Kim CS.
Isocitrate dehydrogenase 2 deficiency induces endothelial inflammation via p66sh-
mediated mitochondrial oxidative stress.
1: Piao Y, Gwon DH, Kang DW, Hwang TW, Shin N, Kwon HH, Shin HJ, Yin Y, Kim JJ, Hong J, Kim HW, Kim Y, Kim SR, Oh SH, Kim DW*.
TLR4-mediated autophagic impairment contributes to neuropathic pain in chronic constriction injury mice.
Mol Brain. 2018 Feb 27;11(1):11.
Mol Brain. 2018 Feb 27;11(1):11.
2. Shin J, Yin Y, Park H, Park S, Triantafillu UL, Kim Y, Kim SR, Lee SY, Kim DK,
Hong J, Kim DW*.
p38 siRNA-encapsulated PLGA nanoparticles alleviate neuropathic pain behavior in rats by inhibiting microglia activation.
Nanomedicine (Lond). 2018 Jul;13(13):1607-1621.
doi: 10.2217/nnm-2018-0054. PubMed PMID: 30028250.
https://goo.gl/rnqfH6
3. Yin Y, Yi MH, Kim DW*.
Impaired Autophagy of GABAergic Interneurons in Neuropathic Pain.
Pain Res Manag. 2018 Sep 25;2018:9185368.
doi: 10.1155/2018/9185368. eCollection 2018. Review. PubMed PMID: 30356379; PubMed Central PMCID: PMC6176324.
p38 siRNA-encapsulated PLGA nanoparticles alleviate neuropathic pain behavior in rats by inhibiting microglia activation.
Nanomedicine (Lond). 2018 Jul;13(13):1607-1621.
doi: 10.2217/nnm-2018-0054. PubMed PMID: 30028250.
https://goo.gl/rnqfH6
3. Yin Y, Yi MH, Kim DW*.
Impaired Autophagy of GABAergic Interneurons in Neuropathic Pain.
Pain Res Manag. 2018 Sep 25;2018:9185368.
doi: 10.1155/2018/9185368. eCollection 2018. Review. PubMed PMID: 30356379; PubMed Central PMCID: PMC6176324.
1: Piao S, Lee JW, Nagar H, Jung SB, Choi S, Kim S, Lee I, Kim SM, Shin N, Lee YR, Lee SD, Park JB, Irani K, Won M, Hur GM, Jeon BH, Kim DW, Kim CS.
CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation.
PLoS One. 2018 Feb 23;13(2):e0192693.
PLoS One. 2018 Feb 23;13(2):e0192693.
2. Leem E, Kim HJ, Choi M, Kim S, Oh YS, Lee KJ, Choe YS, Um JY, Shin WH, Jeong JY, Jin BK, Kim DW, McLean C, Fisher PB, Kholodilov N, Ahn KS, Lee JM, Jung UJ, Lee SG, Kim SR.
Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo.
Cell Death Dis. 2018 Apr 18;9(5):449.
doi: 10.1038/s41419-018-0491-3. PubMed PMID: 29670079.
Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo.
Cell Death Dis. 2018 Apr 18;9(5):449.
doi: 10.1038/s41419-018-0491-3. PubMed PMID: 29670079.
3. Kwon HH, Lee T, Hong J, Kim DW, Kang JW.
Long-term prenatal stress increases
susceptibility of N-methyl-D-aspartic acid-induced spasms in infant rats.
Korean
J Pediatr. 2018 May;61(5):150-155.
doi: 10.3345/kjp.2018.61.5.150. Epub 2018 May
28. PubMed PMID: 29853939; PubMed Central PMCID: PMC5976564.
4. Choi SJ, Piao S, Nagar H, Jung SB, Kim S, Lee I, Kim SM, Song HJ, Shin N, Kim DW, Irani K, Jeon BH, Park JW, Kim CS.
mediated mitochondrial oxidative stress.
Biochem Biophys Res Commun. 2018 Sep 10;503(3):1805-1811.
doi: 10.1016/j.bbrc.2018.07.117. Epub 2018 Jul 30. PubMed PMID: 30072100.
Patent
에반스블루를 포함하는 만성통증 질환 예방 또는 치료용 조성물
출원: 10-2017-0105614 (2017.08.21)
등록: 10-1841951 (2018.03.20)
발명인: 이원형, 김동운, 홍진표, 윤옥화
Astrocytic Expression of CTMP Following an Excitotoxic Lesion in the Mouse Hippocampus.
Exp Neurobiol. 2017 Feb;26(1):25-32.
doi: 10.5607/en.2017.26.1.25. PubMed PMID: 28243164.
2. Zhang E, Kim JJ, Shin N, Yin Y, Nan Y, Xu Y, Hong J, Hsu TM, Chung W, Ko Y,
Lee W, Lim K, Kim DW*, Lee SY.
5. Kwon JY, Jung UJ, Kim DW, Kim S, Moon GJ, Hong J, Jeon MT, Shin M, Chang JH, Kim SR.
Beneficial Effects of Hesperetin in a Mouse Model of Temporal Lobe Epilepsy.
J Med Food. 2018 Aug 23.
doi: 10.1089/jmf.2018.4183. [Epub ahead of print] PubMed PMID: 30136878.
6. Hong B, Lee S, Shin N, Ko Y, Kim D, Lee J, Lee W.
Bone regeneration with umbilical cord blood mesenchymal stem cells in femoral defects of ovariectomized rats.
Osteoporos Sarcopenia. 2018 Sep;4(3):95-101.
doi:10.1016/j.afos.2018.08.003. Epub 2018 Sep 26. PubMed PMID: 30775550; PubMed
Central PMCID: PMC6362973
doi: 10.1089/jmf.2018.4183. [Epub ahead of print] PubMed PMID: 30136878.
6. Hong B, Lee S, Shin N, Ko Y, Kim D, Lee J, Lee W.
Bone regeneration with umbilical cord blood mesenchymal stem cells in femoral defects of ovariectomized rats.
Osteoporos Sarcopenia. 2018 Sep;4(3):95-101.
doi:10.1016/j.afos.2018.08.003. Epub 2018 Sep 26. PubMed PMID: 30775550; PubMed
Central PMCID: PMC6362973
Patent
에반스블루를 포함하는 만성통증 질환 예방 또는 치료용 조성물
출원: 10-2017-0105614 (2017.08.21)
등록: 10-1841951 (2018.03.20)
발명인: 이원형, 김동운, 홍진표, 윤옥화
PINK1을 포함하는 신경병증성 통증 진단용 조성물
Composition for diagnosing neuropathic pain comprising PTEN-induced putative kinase 1
출원: 10-2017-0112675 (2017.09.04)
등록: 10-1847608 (2018.04.04)
김동운, 홍진표, 이민희, 장은희
Patent Transfer to NanoBio company
2018.5.20
Composition for diagnosing neuropathic pain comprising PTEN-induced putative kinase 1
Foxp3 및 CD200 수용체 활성화제를 포함하는 발작성 질환 예방 또는 치료용 약학적 조성물
Composition for preventing or treating diseases related to seizure comprising Foxp3 CD200 Receptor activator
출원: 10-2016-0016981 (2016.02.15)
등록: 10-1884278 (2018.07.26)
김동운, 이민희, 오상하
2017 year
1. Shin N, Yi MH, Kim S, Baek H, Triantafillu UL, Park J, Kim DW*. Composition for diagnosing neuropathic pain comprising PTEN-induced putative kinase 1
출원: 10-2017-0112675 (2017.09.04)
등록: 10-1847608 (2018.04.04)
김동운, 홍진표, 이민희, 장은희
Patent Transfer to NanoBio company
2018.5.20
Composition for diagnosing neuropathic pain comprising PTEN-induced putative kinase 1
Foxp3 및 CD200 수용체 활성화제를 포함하는 발작성 질환 예방 또는 치료용 약학적 조성물
Composition for preventing or treating diseases related to seizure comprising Foxp3 CD200 Receptor activator
출원: 10-2016-0016981 (2016.02.15)
등록: 10-1884278 (2018.07.26)
김동운, 이민희, 오상하
2017 year
Astrocytic Expression of CTMP Following an Excitotoxic Lesion in the Mouse Hippocampus.
Exp Neurobiol. 2017 Feb;26(1):25-32.
doi: 10.5607/en.2017.26.1.25. PubMed PMID: 28243164.
High Omega-3 Polyunsaturated Fatty Acids in fat-1
Mice Reduce Inflammatory Pain.
J Med Food. 2017 Jun;20(6):535-541.
doi:
10.1089/jmf.2016.3871. Epub 2017 Jun 1. PubMed PMID: 28570125.
http://bit.ly/2sA104R
3. Cho SY, Kim SH, Yi MH, Zhang E, Kim E, Park J, Jo EK, Lee YH, Park MS, Kim Y, Park J, Kim DW*.
Expression of PGC1α in glioblastoma multiforme patients.
Oncol Lett. 2017 Jun;13(6):4055-4076.
doi: 10.3892/ol.2017.5972. Epub 2017 Apr 3. PubMed PMID: 28599408; PubMed Central PMCID: PMC5453058.
4. Zhang E, Lee S, Yi MH, Nan Y, Xu Y, Shin N, Ko Y, Lee YH, Lee W, Kim DW*.
http://bit.ly/2sA104R
3. Cho SY, Kim SH, Yi MH, Zhang E, Kim E, Park J, Jo EK, Lee YH, Park MS, Kim Y, Park J, Kim DW*.
Expression of PGC1α in glioblastoma multiforme patients.
Oncol Lett. 2017 Jun;13(6):4055-4076.
doi: 10.3892/ol.2017.5972. Epub 2017 Apr 3. PubMed PMID: 28599408; PubMed Central PMCID: PMC5453058.
Expression of granulocyte colony-stimulating factor 3 receptor in the spinal
dorsal horn following spinal nerve ligation-induced neuropathic pain.
Mol Med
Rep. 2017 Aug;16(2):2009-2015.
doi: 10.3892/mmr.2017.6853. Epub 2017 Jun 23.
PubMed PMID: 28656207
5. Baek H, Shin HJ, Kim JJ, Shin N, Kim S, Yi MH, Zhang E, Hong J, Kang JW, Kim Y, Kim CS, Kim DW*.
5. Baek H, Shin HJ, Kim JJ, Shin N, Kim S, Yi MH, Zhang E, Hong J, Kang JW, Kim Y, Kim CS, Kim DW*.
Primary cilia modulate TLR4-mediated inflammatory responses in
hippocampal neurons.
J Neuroinflammation. 2017 Sep 19;14(1):189.
doi:
10.1186/s12974-017-0958-7. PubMed PMID: 28927423.
http://rdcu.be/v0d7
6. Nagar H, Jung SB, Ryu MJ, Choi SJ, Piao S, Song HJ, Kang SK, Shin N, Kim DW, Jin SA, Jeong JO, Irani K, Jeon BH, Shong M, Kweon GR, Kim CS.
CR6-Interacting Factor 1 Deficiency Impairs Vascular Function by Inhibiting the Sirt1-Endothelial Nitric Oxide Synthase Pathway.
Antioxid Redox Signal. 2017 Aug 1;27(4):234-249.
doi: 10.1089/ars.2016.6719. Epub 2017 May 24. PubMed PMID: 28117598.
http://rdcu.be/v0d7
6. Nagar H, Jung SB, Ryu MJ, Choi SJ, Piao S, Song HJ, Kang SK, Shin N, Kim DW, Jin SA, Jeong JO, Irani K, Jeon BH, Shong M, Kweon GR, Kim CS.
CR6-Interacting Factor 1 Deficiency Impairs Vascular Function by Inhibiting the Sirt1-Endothelial Nitric Oxide Synthase Pathway.
Antioxid Redox Signal. 2017 Aug 1;27(4):234-249.
doi: 10.1089/ars.2016.6719. Epub 2017 May 24. PubMed PMID: 28117598.
7. Gwon DH, Hwang TW, Ro JY, Kang YJ, Jeong JY, Kim DK, Lim K, Kim DW, Choi DE,
Kim JJ.
High Endogenous Accumulation of ω-3 Polyunsaturated Fatty Acids Protect against Ischemia-reperfusion Renal Injury through AMPK-Mediated Autophagy in Fat-1 Mice.
High Endogenous Accumulation of ω-3 Polyunsaturated Fatty Acids Protect against Ischemia-reperfusion Renal Injury through AMPK-Mediated Autophagy in Fat-1 Mice.
Int J Mol Sci. 2017 Sep 30;18(10).
pii: E2081. doi:
10.3390/ijms18102081. PubMed PMID: 28974016.
2. Baek H, Yi MH, Pandit S, Park JB, Kwon HH, Zhang E, Kim S, Shin N, Kim E, Lee YH, Kim Y, Kim DW*, Kang JW.
Altered expression of KCC2 in GABAergic interneuron contributes prenatal stress-induced epileptic spasms in infant rat.
Neurochem Int. 2016 Jul;97:57-64.
doi: 10.1016/j.neuint.2016.05.006. PubMed PMID: 27180051.
3. Choi S, Kwon HJ, Song HJ, Choi SW, Nagar H, Piao S, Jung SB, Jeon BH, Kim DW*, Kim CS.
Nafamostat mesilate promotes endothelium-dependent vasorelaxation via the Akt-eNOS dependent pathway.
Korean J Physiol Pharmacol. 2016 Sep;20(5):539-45.
doi: 10.4196/kjpp.2016.20.5.539. PubMed PMID: 27610041; PubMed Central PMCID: PMC5015001.
6. Lee SD, Yi MH, Kim DW, Lee Y, Choi Y, Oh SH.
The effect of botulinum neurotoxin type A on capsule formation around silicone implants: the in vivo and in vitro study.
Int Wound J. 2016 Feb;13(1):65-71.
doi: 10.1111/iwj.12228. Epub 2014 Mar 7. PubMed PMID: 24602064. ISSN: 1742-4801
7. Suh M, Hyun J, Lye A, Kim DW, Park SJ, Choi JW, Hur G, Park Y
Compensation of vestibular function and plasticity of vestibular nucleus after unilateral ochleostomy.
Neural Plast. 2016;2016:7287180.
doi: 10.1155/2016/7287180. Epub 2016 Jan 12.ISSN: 2090-5904
10. Baek H, Lim CS, Byun HS, Cho HS, Lee YR, Shin YS, Kim HW, Jeon BH, Kim DW, Hong J, Hur GM, Park JB.
The anti-inflammatory role of extranuclear apurinic/apyrimidinic endonuclease 1/redox effector factor-1 in reactive astrocytes.
Mol Brain. 2016 Dec 16;9(1):99.
PubMed PMID: 27986089; PubMed Central PMCID: PMC5162091.
2. Lee CH, Yi MH, Chae DJ, Zhang EJ, Oh SH, Kim DW*
3. Yi MH, Zhang E, Baek H, Kim S, Shin N, Kang JW, Lee S, Oh SH, Kim DW*
Patent
2017. 4. 18 (10-2015-0143193)
Composition comprising GABA transporter-3 inhibitor for treating heart failure
가바 수송체-3억제제를 포함하는 심부전 치료용 조성물
박진봉, 수디퍼, 김현우, 김동운
2016 year
2017. 4. 18 (10-2015-0143193)
Composition comprising GABA transporter-3 inhibitor for treating heart failure
가바 수송체-3억제제를 포함하는 심부전 치료용 조성물
박진봉, 수디퍼, 김현우, 김동운
2016 year
1. Kim S, Ahn M, Piao Y, Ha Y, Choi DK, Yi MH, Shin N, Kim DW*, Oh SH.
Effect of Botulinum Toxin Type A on TGF-β/Smad Pathway Signaling: Implications for Silicone-Induced Capsule Formation.
Plast Reconstr Surg. 2016 Nov;138(5):821e-829e.
PubMed PMID: 27391832.
Plast Reconstr Surg. 2016 Nov;138(5):821e-829e.
PubMed PMID: 27391832.
2. Baek H, Yi MH, Pandit S, Park JB, Kwon HH, Zhang E, Kim S, Shin N, Kim E, Lee YH, Kim Y, Kim DW*, Kang JW.
Altered expression of KCC2 in GABAergic interneuron contributes prenatal stress-induced epileptic spasms in infant rat.
Neurochem Int. 2016 Jul;97:57-64.
doi: 10.1016/j.neuint.2016.05.006. PubMed PMID: 27180051.
3. Choi S, Kwon HJ, Song HJ, Choi SW, Nagar H, Piao S, Jung SB, Jeon BH, Kim DW*, Kim CS.
Nafamostat mesilate promotes endothelium-dependent vasorelaxation via the Akt-eNOS dependent pathway.
Korean J Physiol Pharmacol. 2016 Sep;20(5):539-45.
doi: 10.4196/kjpp.2016.20.5.539. PubMed PMID: 27610041; PubMed Central PMCID: PMC5015001.
4. Yi MH, Zhang E, Kim JJ, Baek H, Shin N, Kim S, Kim SR, Kim HR, Lee SJ, Park JB, Kim Y, Kwon OY, Lee YH, Oh SH, Kim DW*.
CD200R/Foxp3-mediated signalling regulates microglial activation.
Sci Rep. 2016 Oct 12;6:34901.
http://rdcu.be/kUyx
doi: 10.1038/srep34901. PubMed PMID: 27731341; PubMed Central PMCID: PMC5059636.
Sci Rep. 2016 Oct 12;6:34901.
http://rdcu.be/kUyx
doi: 10.1038/srep34901. PubMed PMID: 27731341; PubMed Central PMCID: PMC5059636.
5. Son SW, Lee JS, Kim HG, Kim DW, Ahn YC, Son CG.
Testosterone Depletion Increases the Susceptibility of Brain Tissue to Oxidative Damage in a Restraint Stress Mouse Model.
J Neurochem. 2016 Jan;136(1):106-17.
doi: 10.1111/jnc.13371. Epub 2015 Oct 16. PubMed PMID: 26385432. ISSN: 0022-3042
Testosterone Depletion Increases the Susceptibility of Brain Tissue to Oxidative Damage in a Restraint Stress Mouse Model.
J Neurochem. 2016 Jan;136(1):106-17.
doi: 10.1111/jnc.13371. Epub 2015 Oct 16. PubMed PMID: 26385432. ISSN: 0022-3042
6. Lee SD, Yi MH, Kim DW, Lee Y, Choi Y, Oh SH.
The effect of botulinum neurotoxin type A on capsule formation around silicone implants: the in vivo and in vitro study.
Int Wound J. 2016 Feb;13(1):65-71.
doi: 10.1111/iwj.12228. Epub 2014 Mar 7. PubMed PMID: 24602064. ISSN: 1742-4801
7. Suh M, Hyun J, Lye A, Kim DW, Park SJ, Choi JW, Hur G, Park Y
Compensation of vestibular function and plasticity of vestibular nucleus after unilateral ochleostomy.
Neural Plast. 2016;2016:7287180.
doi: 10.1155/2016/7287180. Epub 2016 Jan 12.ISSN: 2090-5904
8. Kim JJ, Kang YJ, Shin SA, Bak DH, Lee JW, Lee KB, Yoo YC, Kim DK, Lee BH, Kim DW, Lee J, Jo EK, Yuk JM.
Phlorofucofuroeckol Improves Glutamate-Induced Neurotoxicity through Modulation of Oxidative Stress-Mediated Mitochondrial Dysfunction in PC12 Cells.
PLoS One. 2016 Sep 26;11(9):e0163433.
doi: 10.1371/journal.pone.0163433. eCollection 2016. PubMed PMID: 27669570.
http://dx.doi.org/10.1371/journal.pone.0163433
Phlorofucofuroeckol Improves Glutamate-Induced Neurotoxicity through Modulation of Oxidative Stress-Mediated Mitochondrial Dysfunction in PC12 Cells.
PLoS One. 2016 Sep 26;11(9):e0163433.
doi: 10.1371/journal.pone.0163433. eCollection 2016. PubMed PMID: 27669570.
http://dx.doi.org/10.1371/journal.pone.0163433
9. Lim YJ, Yi MH, Choi JA, Lee J, Han JY, Jo SH, Oh SM, Cho HJ, Kim DW, Kang MW, Song CH.
Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections.
Sci Rep. 2016 Nov 15;6:37211.
doi: 10.1038/srep37211. PubMed PMID: 27845414; PubMed Central PMCID: PMC5109032.
Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections.
Sci Rep. 2016 Nov 15;6:37211.
doi: 10.1038/srep37211. PubMed PMID: 27845414; PubMed Central PMCID: PMC5109032.
10. Baek H, Lim CS, Byun HS, Cho HS, Lee YR, Shin YS, Kim HW, Jeon BH, Kim DW, Hong J, Hur GM, Park JB.
The anti-inflammatory role of extranuclear apurinic/apyrimidinic endonuclease 1/redox effector factor-1 in reactive astrocytes.
Mol Brain. 2016 Dec 16;9(1):99.
PubMed PMID: 27986089; PubMed Central PMCID: PMC5162091.
2015 year
1. Yi MH, Kwon K, Zhang E, Seo JH, Kang SS, Son CG, Kang JW, Kim DW*.
RhoGDI2 Expression in Astrocytes After an Excitotoxic Lesion in the Mouse Hippocampus.
Cell Mol Neurobiol. 2015 Mar;35(2):167-74.
doi: 10.1007/s10571-014-0108-z. Epub 2014 Oct 2. PubMed PMID: 25274045.
ISSN: 0272-4340
1. Yi MH, Kwon K, Zhang E, Seo JH, Kang SS, Son CG, Kang JW, Kim DW*.
RhoGDI2 Expression in Astrocytes After an Excitotoxic Lesion in the Mouse Hippocampus.
Cell Mol Neurobiol. 2015 Mar;35(2):167-74.
doi: 10.1007/s10571-014-0108-z. Epub 2014 Oct 2. PubMed PMID: 25274045.
ISSN: 0272-4340
2. Lee CH, Yi MH, Chae DJ, Zhang EJ, Oh SH, Kim DW*
Effect of pioglitazone on excitotoxic neuronal damage in the mouse hippocampus
Biomol Ther (Seoul). 2015 May;23(3):261-7.
doi: 10.4062/biomolther.2014.146. Epub 2015 May 1. PubMed PMID: 25995825; PubMed Central PMCID: PMC4428719. ISSN: 1976-9148
Biomol Ther (Seoul). 2015 May;23(3):261-7.
doi: 10.4062/biomolther.2014.146. Epub 2015 May 1. PubMed PMID: 25995825; PubMed Central PMCID: PMC4428719. ISSN: 1976-9148
3. Yi MH, Zhang E, Baek H, Kim S, Shin N, Kang JW, Lee S, Oh SH, Kim DW*
Growth differentiation factor 15 Expression in Astrocytes After Excitotoxic Lesion in the Mouse Hippocampus.
Exp Neurobiol. 2015 Jun;24(2):133-8.
doi: 10.5607/en.2015.24.2.133. Epub 2015 Mar 30. PubMed PMID: 26113792; PubMed Central PMCID: PMC4479809. ISSN: 1226-2560
4. Zhang E, Yi MH, Shin N, Baek H, Kim S, Lee S, Kim E, Kwon K, Kim H, Bae YC, Lee YH, Kim Y, Kwon O, Lee W, Kim DW*
Endoplasmic reticulum stress impairment in the spinal dorsal horn of a neuropathic pain model.
Sci Rep. 2015 Jun 25;5:11555.
doi: 10.1038/srep11555. PubMed PMID: 26109318; PubMed Central PMCID: PMC4479804.
ISSN: 2045-2322
http://www.nature.com/srep/2015/150625/srep11555/full/srep11555.html
Exp Neurobiol. 2015 Jun;24(2):133-8.
doi: 10.5607/en.2015.24.2.133. Epub 2015 Mar 30. PubMed PMID: 26113792; PubMed Central PMCID: PMC4479809. ISSN: 1226-2560
4. Zhang E, Yi MH, Shin N, Baek H, Kim S, Lee S, Kim E, Kwon K, Kim H, Bae YC, Lee YH, Kim Y, Kwon O, Lee W, Kim DW*
Endoplasmic reticulum stress impairment in the spinal dorsal horn of a neuropathic pain model.
Sci Rep. 2015 Jun 25;5:11555.
doi: 10.1038/srep11555. PubMed PMID: 26109318; PubMed Central PMCID: PMC4479804.
ISSN: 2045-2322
http://www.nature.com/srep/2015/150625/srep11555/full/srep11555.html
6. Kwon SK, Ahn M, Song H, Kang SK, Jung S, Harsha, Lee S, Moon JY, Suh K, Lee SD, Jeon BH, Kim DW*, Kim CS.
Nafamostat mesilate attenuates transient focal ischemia/reperfusion-induced brain injury via the inhibition of endoplasmic reticulum stress.
Brain Res. 2015 Nov 19;1627:12-20.
doi: 10.1016/j.brainres.2015.09.013. Epub 2015 Sep 24. PubMed PMID: 26390938.
ISSN: 0006-8993
6. Bak DH, Zhang E, Yi M, Kim D, Lim K, Kim J, Kim DW*
High ω3-polyunsaturated fatty acids in fat-1 mice prevent streptozotocin-induced Purkinje cell degeneration through BDNF-mediated autophagy
Sci Rep. 2015 Oct 27;5:15465.
doi: 10.1038/srep15465. PubMed PMID: 26503303; PubMed Central PMCID: PMC4621527.
ISSN: 2045-2322
http://www.nature.com/articles/srep15465
* Patent
특허번호: 10-1482908
등록일: 2015년 1월 8일 등록
발명의 명칭: 간질중첩증 진단용 바이오마커 조성물
발명자: 김동운, 박진봉, 강준원, 이민희
** Technology Transfer (기술이전)
협약일: 2015년 4월 24일
충남대학교산학협력단-EVER Neuro Pharma (Asia) Ltd.
세레브로리신을 유효성분으로 함유하는 만성외상성뇌병증 예방 또는 치료용 조성물
- 출원번호: 10-2014-0030304 (2014.03.14)
*** Award
제65회 대한해부학회 한곡학술상 빛날상(2015-1-04)
2015년 10월 16일
2014 year
1: Lee WY, Jang SW, Lee JS, Kim YH, Kim HG, Han JM, Kim DW, Yi MH, Choi MK, Son
CG.
Uwhangchungsimwon, a traditional herbal medicine, protects brain against
oxidative injury via modulation of hypothalamus-pituitary-adrenal (HPA) response
in a chronic restraint mice model.
J Ethnopharmacol. 2014;151(1):461-9.
doi:10.1016/j.jep.2013.10.066. Epub 2013 Nov 20. PubMed PMID: 24269337. ISSN: 0378-8741
2: Kim JY, Lee EY, Sohn HJ, Kim DW, Cho SS, Seo JH.
Sequential accumulation of iron in glial cells during chicken cerebellar development.
Acta Histochem. 2014 May;116(4):570-6.
doi: 10.1016/j.acthis.2013.11.003. Epub 2013 Dec 19. PubMed PMID: 24360020.
ISSN: 0065-1281
3: Jin J, Rha KS, Kim DW*, Kim YM.
IL-17C expression in nasal epithelial cells of chronic rhinosinusitis with nasal polyposis.
Eur Arch Otorhinolaryngol. 2014 May;271(5):1097-105.
doi: 10.1007/s00405-013-2683-x. Epub 2013 Sep 7. PubMed PMID: 24013453.
ISSN: 0937-4477
4: Lee JS, Kim HG, Han JM, Kim DW, Yi MH, Son SW, Kim YA, Lee JS, Choi MK, Son
CG.
Ethanol extract of Astragali Radix and Salviae Miltiorrhizae Radix, Myelophil, exerts anti-amnesic effect in a mouse model of scopolamine-induced memory deficits.
J Ethnopharmacol. 2014 May 14;153(3):782-92.
doi: 10.1016/j.jep.2014.03.048. Epub 2014 Mar 30. PubMed PMID: 24690775. ISSN: 0378-8741
Patent
Composition containing 3-methyladenine (3-MA) for treatement or improvement of neuropathic pain
3-메틸아데닌을 유효성분으로 포함하는 신경병증성통증 치료제 또는 개선용 조성물
특허등록번호: 10-1448155
등록일: 2014년 9월 30일
발명자: 김동운, 이원형, 장은희
특허출원: 세레브로리신을 유효성분으로 함유하는 만성외상성뇌병증 예방 또는 치료용 조성물
발명자: 김동운, 송희정
출원번호: 10-2014-0030304
2013 year
1. Yi MH, Lee YS, Kang JW, Kim SJ, Oh SH, Kim YM, Lee YH, Lee SD, Kim DW*
NFAT5-Dependent Expression of AQP4 in Astrocytes.
Cell Mol Neurobiol. 2013 Mar;33(2):223-32.
ISSN: 0272-4340
2. Kim JY, Lee EY, Sohn HJ, Kim SW, Kim CH, Ahn HY, Kim DW, Cho SS, Seo JH.
Differential expression of αB-crystallin causes maturation-dependent susceptibility of oligodendrocytes to oxidative stress.
BMB Rep. 2013 Oct;46(10):501-6.
ISSN: 1976-6696
3. Pandit S, Jeong JA, Jo JY, Cho HS, Kim DW, Kim JM, Ryu PD, Lee SY, Kim HW, Jeon BH, Park JB
Dual mechanisms diminishing tonic GABAA inhibition of dentate gyrus granule cells in Noda epileptic rats
J Neurophysiol. 2013 Jul;110(1):95-102.
ISSN: 0022-3077
4. Zhang E, Yi MH, Ko Y, Kim HW, Seo JH, Lee YH, Lee W, Kim DW*
Expression of LC3 and Beclin 1 in the spinal dorsal horn following spinal nerve ligation-induced neuropathic pain
Brain Res. 2013 Jun 26;1519:31-9.
ISSN: 0006-8993
5. Yi MH, Kim S, Zhang E, Kang JW, Park JB, Lee YH, Chung CK, Kim YM, Kim DW*.
IQGAP1 Expression in Spared CA1 Neurons After an Excitotoxic Lesion in the Mouse Hippocampus.
Cell Mol Neurobiol. 2013 Oct;33(7):1003-12.
ISSN: 0272-4340
6. Park J, Kwon K, Kim SH, Yi MH, Zhang E, Kong G, Kim DW*, Park J.
Astrocytic phosphorylation of PDK1 on Tyr9 following an excitotoxic lesion in the mouse hippocampus.
Brain Res. 2013 Oct 2;1533:37-43.
ISSN: 0006-8993
7. Kang HB, Kim G, Kim H, Han SR, Chae DJ, Song H, Kim DW*.
Cerebrolysin Attenuates Astrocyte Activation Following Repetitive Mild Traumatic Brain Injury: Implications for Chronic Traumatic Encephalopathy.
J Life Sci 2013; 23(9); 1096~1103.
ISSN: 1225-9918
2012 year
1. Yi MH, Zhang E, Kang JW, Shin YN, Byun JY, Oh SH, Seo JH, Lee YH, Kim DW*.
Expression of CD200 in alternative activation of microglia following an excitotoxic lesion in the mouse hippocampus.
Brain Res. 2012 Oct 24;1481:90-6.
2. Jin J, Lee JW, Rha KS, Kim DW, Kim YM.
Expression pattern of IQGAP1 in sinonasal inverted papillomas and squamous cell carcinomas.
Laryngoscope. 2012 Jul 25.
3. Kim JY, Song SH, Kim HN, Kim DW, Sohn HJ, Lee EY, Cho SS, Seo JH.
ΑB-crystallin is expressed in myelinating oligodendrocytes of the developing and adult avian retina.
Neurochem Res. 2012 Oct;37(10):2135-42.
4. Oh SH, Choi S, Kim DW, Jeong JY.
Intranasal approach for manipulating the depressor septi nasi.
J Craniofac Surg. 2012 Mar;23(2):367-9.
5. Kang JW, Kim DW, Lee YS, Lee YH, Lee KS.
Polymorphism of SCN1A and SCN2A Gene in Pediatric Refractory Epilepsy Patients.
J Korean Epilepsy Soc. 2012 Dec;16(2):49-55.
6. Nam IH, Kim DW, Song HJ, Kim S, Lee KS, Lee YH.
Association of Corpora Amylacea Formation with Astrocytes and Cerebrospinal Fluid in the Aged Human Brain.
Korean J Phys Anthropol. 2012 Dec;25(4):177-184.
7. Kwon K, Kwon Y, Kim S, Kim DW, Kwon O.
Regulation of Endoplasmic Reticulum Stress Response by the Immobilization Stress.
Journal of Life Science 2012 Vol. 22. No. 8. 1132~1136.
2011 year
1. Jeong HJ, Jeong HW, Song SS, Kang JW, Seo JH, Lee YH, Lee KS, Kim DW*.
Upregulation of Peroxiredeoxin III in the hippocampus of acute immobilization stress model rats and the Foxo3a-dependent expression in PC12 cells.
Cell Mol Neurobiol. 2011 Oct;31(7):1041-6.
2. Lee YS, Kim DW, Lee YH, Oh JH, Yoon S, Choi MS, Lee SK, Kim JW, Lee K, Song CW.
Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells.
Arch Toxicol. 2011 Dec;85(12):1529-40.
3. Lee YS, Kang JW, Lee YH, Kim DW*.
ID4 mediates proliferation of astrocytes after excitotoxic damage in the mouse hippocampus.
Anat Cell Biol. 2011 Jun;44(2):128-34.
4. Yang WM, Jung KJ, Lee MO, Lee YS, Lee YH, Nakagawa S, Niwa M, Cho SS, Kim DW*.
Transient expression of iron transport proteins in the capillary of the developing rat brain.
Cell Mol Neurobiol. 2011 Jan;31(1):93-9.
5. Oh SH, Kyung HW, Kang N, Seo YJ, Kim DW.
The vascular system of the superior auricular artery: anatomical study and clinical application.
Dermatol Surg. 2011 Jan;37(1):65-72.
6. Kim JY, Sohn HJ, Lee EY, Goo YS, Kim DW, Seo JH.
Expression of αB-crystallin in the peripapillary glial cells of the developing chick retina.
Neurochem Res. 2011 Jan;36(1):76-82.
7. Jung KJ, Kim DW*, Lee HN, Lee YS, Lee SJ, Che JH, Lee YH, Kang BC.
The role of endothelin receptor A during myelination of developing oligodendrocytes.
J Korean Med Sci. 2011 Jan;26(1):92-9
Published Journal (*first or corresponding author): ~ to 2010
1. Lee YS, Kim DW, Kim S, Choi HI, Lee Y, Kim CD, Lee JH, Lee SD, Lee YH. Downregulation of NFAT2 promotes melanogenesis in B16 melanoma cells.
Anat Cell Biol. 2010 Dec;43(4):303-9.
2. Lee HN, Jeon GS, Kim DW, Cho IH, Cho SS. Expression of adenomatous polyposis coli protein in reactive astrocytes in hippocampus of kainic acid-induced rat.
Neurochem Res. 2010 Jan;35(1):114-21.
3. Cho IH, Hong J, Suh EC, Kim JH, Lee H, Lee JE, Lee S, Kim CH, Kim DW, Jo EK, Lee KE, Karin M, Lee SJ.
Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death. Brain. 2008 Nov;131(Pt 11):3019-33.
4. Jeon GS, Choi DH, Lee HN, Kim DW, Chung CK, Cho SS.
Expression of L-serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase (Phgdh) and neutral amino acid transporter ASCT1 following an excitotoxic lesion in the mouse hippocampus. Neurochem Res. 2009 May;34(5):827-34.
5. Kim DW*, Lee HN, Song JE, Jung KJ, Yang WM, Kwon K, Jeon GS, Lee YH, Chung CK, Cho SS.
Expression of transferrin binding protein in the capillaries of the brain in the developing chick embryo. Neurochem Res. 2008 Nov;33(11):2288-93.
6. Seo JH, Chang JH, Song SH, Lee HN, Jeon GS, Kim DW, Chung CK, Cho SS. Spatiotemporal gradient of astrocyte development in the chick optic tectum: evidence for multiple origins and migratory paths of astrocytes.
Neurochem Res. 2008 Jul;33(7):1346-55.
7. Jeon GS, Park SK, Park SW, Kim DW, Chung CK, Cho SS.
Glial expression of interleukin-18 and its receptor after excitotoxic damage in the mouse hippocampus. Neurochem Res. 2008 Jan;33(1):179-84.
8. Kim DW*, Lee JH, Park SK, Yang WM, Jeon GS, Lee YH, Chung CK, Cho SS. Astrocytic expressions of phosphorylated Akt, GSK3beta and CREB following an excitotoxic lesion in the mouse hippocampus.
Neurochem Res. 2007 Sep;32(9):1460-8.
9. Park SW, Lim HS, Roh EJ, Kim DW, Jeon GS, Cho SS.
Developmental expression of transferrin binding protein in oligodendrocyte lineage cells of the embryonic chick spinal cord. Neurochem Res. 2007 Jan;32(1):11-8.
10. Jeon GS, Byun HJ, Park SK, Park SW, Kim DW, Seo JH, Cha CI, Cho SS.
Induction of transcription factor A-myb expression in reactive astrocytes following an excitotoxic lesion in the mouse hippocampus. Neurochem Res. 2006 Nov;31(11):1371-4.
11. Kim DW*, Park SW, Jeon GS, Seo JH, Golden JA, Cho SS.
The multiple dorsoventral origins and migratory pathway of tectal oligodendrocytes in the developing chick. Brain Res. 2006 Mar 3;1076(1):16-24.
12. Kim DW*, Chang JH, Park SW, Jeon GS, Seo JH, Cho SS.
Activated cyclic AMP-response element binding protein (CREB) is expressed in a myelin-associated protein in chick. Neurochem Res. 2005 Sep;30(9):1133-7.
13. Kim DW*, Ahn TB, Kim JM, Jeon GS, Seo JH, Jeon BS, Cho SS.
Enhanced Mn-SOD immunoreactivity in the dopaminergic neurons of long-evans cinnamon rats. Neurochem Res. 2005 Apr;30(4):475-8.
14. Ahn TB, Cho SS, Kim DW, Jeon BS. Absence of nigrostriatal degeneration in LEC rats up to 20 weeks of age. Neurol Res. 2005 Jun;27(4):409-11. .
15. Kim JM, Ko SB, Kwon SJ, Kim HJ, Han MK, Kim DW, Cho SS, Jeon BS.
Ferrous and ferric iron accumulates in the brain of aged Long-Evans Cinnamon rats, an animal model of Wilson's disease. Neurosci Lett. 2005 Jul 1-8;382(1-2):143-7.
16. Jeon GS, Park SW, Kim DW, Seo JH, Cho J, Lim SY, Kim SD, Cho SS.
Glial expression of the 90-kDa heat shock protein (HSP90) and the 94-kDa glucose-regulated protein (GRP94) following an excitotoxic lesion in the mouse hippocampus.
Glia. 2004 Nov 15;48(3):250-8. P
17. Jeon GS, Kang TC, Park SW, Kim DW, Seo JH, Cho SS. Microglial responses in the avascular quail retina following transection of the optic nerve.
Brain Res. 2004 Oct 8;1023(1):15-23.
18. Lee C, Kim DW, Jeon GS, Roh EJ, Seo JH, Wang KC, Cho SS. Cerebellar alterations induced by chronic hypoxia: an immunohistochemical study using a chick embryonic model.
Brain Res. 2001 May 18;901(1-2):271-6.
19. Seo JH, Haam YG, Park SW, Kim DW, Jeon GS, Lee C, Hwang DH, Kim YS, Cho SS.
Oligodendroglia in the avian retina: immunocytochemical demonstration in the adult bird.
J Neurosci Res. 2001 Jul 15;65(2):173-83.
Nafamostat mesilate attenuates transient focal ischemia/reperfusion-induced brain injury via the inhibition of endoplasmic reticulum stress.
Brain Res. 2015 Nov 19;1627:12-20.
doi: 10.1016/j.brainres.2015.09.013. Epub 2015 Sep 24. PubMed PMID: 26390938.
ISSN: 0006-8993
6. Bak DH, Zhang E, Yi M, Kim D, Lim K, Kim J, Kim DW*
High ω3-polyunsaturated fatty acids in fat-1 mice prevent streptozotocin-induced Purkinje cell degeneration through BDNF-mediated autophagy
Sci Rep. 2015 Oct 27;5:15465.
doi: 10.1038/srep15465. PubMed PMID: 26503303; PubMed Central PMCID: PMC4621527.
ISSN: 2045-2322
http://www.nature.com/articles/srep15465
7. Min H, Hong J, Cho IH, Jang YH, Lee H, Kim DW, Yu SW, Lee S, Lee SJ.
TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates intracerebral hemorrhage in animal models
Mol Brain. 2015 Apr 10;8:23.
doi: 10.1186/s13041-015-0116-z. PubMed PMID: 25879213; PubMed Central PMCID: PMC4397689. ISSN: 1756-6606
8. Lee JS, Kim HG, Lee HW, Han JM, Lee SK, Kim DW, Saravanakumar A, Son CG
Hippocampal memory enhancing activity of pine needle in scopolamine-induced mouse model
Sci Rep. 2015 May 14;5:9651.
doi: 10.1038/srep09651. PubMed PMID: 25974329; PubMed Central PMCID: PMC4431316.
ISSN: 2045-2322
TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates intracerebral hemorrhage in animal models
Mol Brain. 2015 Apr 10;8:23.
doi: 10.1186/s13041-015-0116-z. PubMed PMID: 25879213; PubMed Central PMCID: PMC4397689. ISSN: 1756-6606
8. Lee JS, Kim HG, Lee HW, Han JM, Lee SK, Kim DW, Saravanakumar A, Son CG
Hippocampal memory enhancing activity of pine needle in scopolamine-induced mouse model
Sci Rep. 2015 May 14;5:9651.
doi: 10.1038/srep09651. PubMed PMID: 25974329; PubMed Central PMCID: PMC4431316.
ISSN: 2045-2322
9. Hwang HY, Zhang E, Park S, Chung W, Lee S, Kim DW, Ko Y, Lee W.
TWIK-Related Spinal Cord K⁺ Channel Expression Is Increased in the Spinal Dorsal Horn after Spinal Nerve Ligation.
Yonsei Med J. 2015 Sep;56(5):1307-15
ISSN: 0513-5796
Yonsei Med J. 2015 Sep;56(5):1307-15
ISSN: 0513-5796
* Patent
특허번호: 10-1482908
등록일: 2015년 1월 8일 등록
발명의 명칭: 간질중첩증 진단용 바이오마커 조성물
발명자: 김동운, 박진봉, 강준원, 이민희
** Technology Transfer (기술이전)
협약일: 2015년 4월 24일
충남대학교산학협력단-EVER Neuro Pharma (Asia) Ltd.
세레브로리신을 유효성분으로 함유하는 만성외상성뇌병증 예방 또는 치료용 조성물
- 출원번호: 10-2014-0030304 (2014.03.14)
*** Award
제65회 대한해부학회 한곡학술상 빛날상(2015-1-04)
2015년 10월 16일
2014 year
1: Lee WY, Jang SW, Lee JS, Kim YH, Kim HG, Han JM, Kim DW, Yi MH, Choi MK, Son
CG.
Uwhangchungsimwon, a traditional herbal medicine, protects brain against
oxidative injury via modulation of hypothalamus-pituitary-adrenal (HPA) response
in a chronic restraint mice model.
J Ethnopharmacol. 2014;151(1):461-9.
doi:10.1016/j.jep.2013.10.066. Epub 2013 Nov 20. PubMed PMID: 24269337. ISSN: 0378-8741
2: Kim JY, Lee EY, Sohn HJ, Kim DW, Cho SS, Seo JH.
Sequential accumulation of iron in glial cells during chicken cerebellar development.
Acta Histochem. 2014 May;116(4):570-6.
doi: 10.1016/j.acthis.2013.11.003. Epub 2013 Dec 19. PubMed PMID: 24360020.
ISSN: 0065-1281
3: Jin J, Rha KS, Kim DW*, Kim YM.
IL-17C expression in nasal epithelial cells of chronic rhinosinusitis with nasal polyposis.
Eur Arch Otorhinolaryngol. 2014 May;271(5):1097-105.
doi: 10.1007/s00405-013-2683-x. Epub 2013 Sep 7. PubMed PMID: 24013453.
ISSN: 0937-4477
4: Lee JS, Kim HG, Han JM, Kim DW, Yi MH, Son SW, Kim YA, Lee JS, Choi MK, Son
CG.
Ethanol extract of Astragali Radix and Salviae Miltiorrhizae Radix, Myelophil, exerts anti-amnesic effect in a mouse model of scopolamine-induced memory deficits.
J Ethnopharmacol. 2014 May 14;153(3):782-92.
doi: 10.1016/j.jep.2014.03.048. Epub 2014 Mar 30. PubMed PMID: 24690775. ISSN: 0378-8741
Patent
Composition containing 3-methyladenine (3-MA) for treatement or improvement of neuropathic pain
3-메틸아데닌을 유효성분으로 포함하는 신경병증성통증 치료제 또는 개선용 조성물
특허등록번호: 10-1448155
등록일: 2014년 9월 30일
발명자: 김동운, 이원형, 장은희
특허출원: 세레브로리신을 유효성분으로 함유하는 만성외상성뇌병증 예방 또는 치료용 조성물
발명자: 김동운, 송희정
출원번호: 10-2014-0030304
2013 year
1. Yi MH, Lee YS, Kang JW, Kim SJ, Oh SH, Kim YM, Lee YH, Lee SD, Kim DW*
NFAT5-Dependent Expression of AQP4 in Astrocytes.
Cell Mol Neurobiol. 2013 Mar;33(2):223-32.
ISSN: 0272-4340
2. Kim JY, Lee EY, Sohn HJ, Kim SW, Kim CH, Ahn HY, Kim DW, Cho SS, Seo JH.
Differential expression of αB-crystallin causes maturation-dependent susceptibility of oligodendrocytes to oxidative stress.
BMB Rep. 2013 Oct;46(10):501-6.
ISSN: 1976-6696
3. Pandit S, Jeong JA, Jo JY, Cho HS, Kim DW, Kim JM, Ryu PD, Lee SY, Kim HW, Jeon BH, Park JB
Dual mechanisms diminishing tonic GABAA inhibition of dentate gyrus granule cells in Noda epileptic rats
J Neurophysiol. 2013 Jul;110(1):95-102.
ISSN: 0022-3077
4. Zhang E, Yi MH, Ko Y, Kim HW, Seo JH, Lee YH, Lee W, Kim DW*
Expression of LC3 and Beclin 1 in the spinal dorsal horn following spinal nerve ligation-induced neuropathic pain
Brain Res. 2013 Jun 26;1519:31-9.
ISSN: 0006-8993
5. Yi MH, Kim S, Zhang E, Kang JW, Park JB, Lee YH, Chung CK, Kim YM, Kim DW*.
IQGAP1 Expression in Spared CA1 Neurons After an Excitotoxic Lesion in the Mouse Hippocampus.
Cell Mol Neurobiol. 2013 Oct;33(7):1003-12.
ISSN: 0272-4340
6. Park J, Kwon K, Kim SH, Yi MH, Zhang E, Kong G, Kim DW*, Park J.
Astrocytic phosphorylation of PDK1 on Tyr9 following an excitotoxic lesion in the mouse hippocampus.
Brain Res. 2013 Oct 2;1533:37-43.
ISSN: 0006-8993
7. Kang HB, Kim G, Kim H, Han SR, Chae DJ, Song H, Kim DW*.
Cerebrolysin Attenuates Astrocyte Activation Following Repetitive Mild Traumatic Brain Injury: Implications for Chronic Traumatic Encephalopathy.
J Life Sci 2013; 23(9); 1096~1103.
ISSN: 1225-9918
2012 year
1. Yi MH, Zhang E, Kang JW, Shin YN, Byun JY, Oh SH, Seo JH, Lee YH, Kim DW*.
Expression of CD200 in alternative activation of microglia following an excitotoxic lesion in the mouse hippocampus.
Brain Res. 2012 Oct 24;1481:90-6.
2. Jin J, Lee JW, Rha KS, Kim DW, Kim YM.
Expression pattern of IQGAP1 in sinonasal inverted papillomas and squamous cell carcinomas.
Laryngoscope. 2012 Jul 25.
3. Kim JY, Song SH, Kim HN, Kim DW, Sohn HJ, Lee EY, Cho SS, Seo JH.
ΑB-crystallin is expressed in myelinating oligodendrocytes of the developing and adult avian retina.
Neurochem Res. 2012 Oct;37(10):2135-42.
4. Oh SH, Choi S, Kim DW, Jeong JY.
Intranasal approach for manipulating the depressor septi nasi.
J Craniofac Surg. 2012 Mar;23(2):367-9.
5. Kang JW, Kim DW, Lee YS, Lee YH, Lee KS.
Polymorphism of SCN1A and SCN2A Gene in Pediatric Refractory Epilepsy Patients.
J Korean Epilepsy Soc. 2012 Dec;16(2):49-55.
6. Nam IH, Kim DW, Song HJ, Kim S, Lee KS, Lee YH.
Association of Corpora Amylacea Formation with Astrocytes and Cerebrospinal Fluid in the Aged Human Brain.
Korean J Phys Anthropol. 2012 Dec;25(4):177-184.
7. Kwon K, Kwon Y, Kim S, Kim DW, Kwon O.
Regulation of Endoplasmic Reticulum Stress Response by the Immobilization Stress.
Journal of Life Science 2012 Vol. 22. No. 8. 1132~1136.
2011 year
1. Jeong HJ, Jeong HW, Song SS, Kang JW, Seo JH, Lee YH, Lee KS, Kim DW*.
Upregulation of Peroxiredeoxin III in the hippocampus of acute immobilization stress model rats and the Foxo3a-dependent expression in PC12 cells.
Cell Mol Neurobiol. 2011 Oct;31(7):1041-6.
2. Lee YS, Kim DW, Lee YH, Oh JH, Yoon S, Choi MS, Lee SK, Kim JW, Lee K, Song CW.
Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells.
Arch Toxicol. 2011 Dec;85(12):1529-40.
3. Lee YS, Kang JW, Lee YH, Kim DW*.
ID4 mediates proliferation of astrocytes after excitotoxic damage in the mouse hippocampus.
Anat Cell Biol. 2011 Jun;44(2):128-34.
4. Yang WM, Jung KJ, Lee MO, Lee YS, Lee YH, Nakagawa S, Niwa M, Cho SS, Kim DW*.
Transient expression of iron transport proteins in the capillary of the developing rat brain.
Cell Mol Neurobiol. 2011 Jan;31(1):93-9.
5. Oh SH, Kyung HW, Kang N, Seo YJ, Kim DW.
The vascular system of the superior auricular artery: anatomical study and clinical application.
Dermatol Surg. 2011 Jan;37(1):65-72.
6. Kim JY, Sohn HJ, Lee EY, Goo YS, Kim DW, Seo JH.
Expression of αB-crystallin in the peripapillary glial cells of the developing chick retina.
Neurochem Res. 2011 Jan;36(1):76-82.
7. Jung KJ, Kim DW*, Lee HN, Lee YS, Lee SJ, Che JH, Lee YH, Kang BC.
The role of endothelin receptor A during myelination of developing oligodendrocytes.
J Korean Med Sci. 2011 Jan;26(1):92-9
Published Journal (*first or corresponding author): ~ to 2010
1. Lee YS, Kim DW, Kim S, Choi HI, Lee Y, Kim CD, Lee JH, Lee SD, Lee YH. Downregulation of NFAT2 promotes melanogenesis in B16 melanoma cells.
Anat Cell Biol. 2010 Dec;43(4):303-9.
2. Lee HN, Jeon GS, Kim DW, Cho IH, Cho SS. Expression of adenomatous polyposis coli protein in reactive astrocytes in hippocampus of kainic acid-induced rat.
Neurochem Res. 2010 Jan;35(1):114-21.
3. Cho IH, Hong J, Suh EC, Kim JH, Lee H, Lee JE, Lee S, Kim CH, Kim DW, Jo EK, Lee KE, Karin M, Lee SJ.
Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death. Brain. 2008 Nov;131(Pt 11):3019-33.
4. Jeon GS, Choi DH, Lee HN, Kim DW, Chung CK, Cho SS.
Expression of L-serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase (Phgdh) and neutral amino acid transporter ASCT1 following an excitotoxic lesion in the mouse hippocampus. Neurochem Res. 2009 May;34(5):827-34.
5. Kim DW*, Lee HN, Song JE, Jung KJ, Yang WM, Kwon K, Jeon GS, Lee YH, Chung CK, Cho SS.
Expression of transferrin binding protein in the capillaries of the brain in the developing chick embryo. Neurochem Res. 2008 Nov;33(11):2288-93.
6. Seo JH, Chang JH, Song SH, Lee HN, Jeon GS, Kim DW, Chung CK, Cho SS. Spatiotemporal gradient of astrocyte development in the chick optic tectum: evidence for multiple origins and migratory paths of astrocytes.
Neurochem Res. 2008 Jul;33(7):1346-55.
7. Jeon GS, Park SK, Park SW, Kim DW, Chung CK, Cho SS.
Glial expression of interleukin-18 and its receptor after excitotoxic damage in the mouse hippocampus. Neurochem Res. 2008 Jan;33(1):179-84.
8. Kim DW*, Lee JH, Park SK, Yang WM, Jeon GS, Lee YH, Chung CK, Cho SS. Astrocytic expressions of phosphorylated Akt, GSK3beta and CREB following an excitotoxic lesion in the mouse hippocampus.
Neurochem Res. 2007 Sep;32(9):1460-8.
9. Park SW, Lim HS, Roh EJ, Kim DW, Jeon GS, Cho SS.
Developmental expression of transferrin binding protein in oligodendrocyte lineage cells of the embryonic chick spinal cord. Neurochem Res. 2007 Jan;32(1):11-8.
10. Jeon GS, Byun HJ, Park SK, Park SW, Kim DW, Seo JH, Cha CI, Cho SS.
Induction of transcription factor A-myb expression in reactive astrocytes following an excitotoxic lesion in the mouse hippocampus. Neurochem Res. 2006 Nov;31(11):1371-4.
11. Kim DW*, Park SW, Jeon GS, Seo JH, Golden JA, Cho SS.
The multiple dorsoventral origins and migratory pathway of tectal oligodendrocytes in the developing chick. Brain Res. 2006 Mar 3;1076(1):16-24.
12. Kim DW*, Chang JH, Park SW, Jeon GS, Seo JH, Cho SS.
Activated cyclic AMP-response element binding protein (CREB) is expressed in a myelin-associated protein in chick. Neurochem Res. 2005 Sep;30(9):1133-7.
13. Kim DW*, Ahn TB, Kim JM, Jeon GS, Seo JH, Jeon BS, Cho SS.
Enhanced Mn-SOD immunoreactivity in the dopaminergic neurons of long-evans cinnamon rats. Neurochem Res. 2005 Apr;30(4):475-8.
14. Ahn TB, Cho SS, Kim DW, Jeon BS. Absence of nigrostriatal degeneration in LEC rats up to 20 weeks of age. Neurol Res. 2005 Jun;27(4):409-11. .
15. Kim JM, Ko SB, Kwon SJ, Kim HJ, Han MK, Kim DW, Cho SS, Jeon BS.
Ferrous and ferric iron accumulates in the brain of aged Long-Evans Cinnamon rats, an animal model of Wilson's disease. Neurosci Lett. 2005 Jul 1-8;382(1-2):143-7.
16. Jeon GS, Park SW, Kim DW, Seo JH, Cho J, Lim SY, Kim SD, Cho SS.
Glial expression of the 90-kDa heat shock protein (HSP90) and the 94-kDa glucose-regulated protein (GRP94) following an excitotoxic lesion in the mouse hippocampus.
Glia. 2004 Nov 15;48(3):250-8. P
17. Jeon GS, Kang TC, Park SW, Kim DW, Seo JH, Cho SS. Microglial responses in the avascular quail retina following transection of the optic nerve.
Brain Res. 2004 Oct 8;1023(1):15-23.
18. Lee C, Kim DW, Jeon GS, Roh EJ, Seo JH, Wang KC, Cho SS. Cerebellar alterations induced by chronic hypoxia: an immunohistochemical study using a chick embryonic model.
Brain Res. 2001 May 18;901(1-2):271-6.
19. Seo JH, Haam YG, Park SW, Kim DW, Jeon GS, Lee C, Hwang DH, Kim YS, Cho SS.
Oligodendroglia in the avian retina: immunocytochemical demonstration in the adult bird.
J Neurosci Res. 2001 Jul 15;65(2):173-83.